기능성 나노의약 연구실
Functional Nanomedicine Laboratory
방문자수
[2023]
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Kim D, Nam SS, Jeon H, Cho Y, Sim E, Kim H*, Phospholipid-based Nanodrill Technology for Enhanced Intracellular Delivery of Nano-Sized Cargos, Smart Materials in Medicine, Smart Materials in Medicine (Accepted)
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Han E, Kim D, Cho Y, Lee S, Kim J, Kim H*, Development of Polymersomes Co-Delivering Doxorubicin and Melittin to Overcome Multidrug Resistance, Molecules 2023, 28, 1087
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Kim H, Kim D, Jang Y, Han H, Lee S, Moon H, Kim J, Kim H*, Development of a Polymersome-Based Nanomedicine for Chemotherapeutic and Sonodynamic Combination Therapy, Int. J. Mol. Sci. 2022, 24, 1194
[2021]
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Jung J, Jang Y, Kim M, Kim H*, Types/Applications of Photoacoustic Contrast Agents: a review, Photonoics 2021, 8, 287
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Kim H, Han H, Hong HK, Park JH, Park KH, Kim H*, Woo SJ*, Permeability of the Retina and RPE-Choroid-Sclera to Three Ophthalmic Drugs and the Associated Factors, Pharmaceutics (Accepted) [IF=4.699]
* Co-corresponding Author
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Keum C, Hong J, Kim D, Lee S-Y*, Kim H*, Lysosome-instructed self-assembly of amino-acid-functionalized perylene diimide for multidrug-resistant cancer cells, ACS Applied Materials & Interfaces. 2021, 13, 13, 14866-14874 [IF=8.758]
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Jang Y, Kim H, Yoon S, Lee H, Hwang J, Jung J, Chang JH*, Choi J*, Kim H*, Exosome-based Photoacoustic Imaging Guided Photodynamic and Immunotherapy for the Treatment of Pancreatic Cancer, J Control Release. 2021 Feb 10; 330:293-304 [상위 3.3%]
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Kim D, Lee JH, Moom H, Seo M, Han H, Yoo H, Seo H, Lee J, Hong S, Kim P, Lee HJ, Chung JW, Kim H*, Development and evaluation of an ultrasound-triggered microbubble combined transaterial chemoembolization (TACE) formulation on rabbit VX2 liver cancer model, Theranostics 2021; 11(1): 79-92 doi:10.7150/thno.45348 [상위 0.9%]
[2020]
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Kim H, Lee H, Kim H, Chang JH, Elimination of Non-targeted Photoacoustic Signals for Combined Photoacoustic and Ultrasound Imaging, IEEE Transactions on Ultrasonics, Ferroelecrics, and Frequency Control [Accepted]
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Choi Y, Han H, Jeon S, Yoon HY, Kim H, Kwon IC, Kim K, Tumor Penetration of Doxorubicin loaded Glycol Chitosan Nanoparticles using High Intensity Focused Ultrasound, Pharmaceutics 2020, 12, 974;doi: 10.3390/pharmaceutics12100974 [IF 4.421]
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Kim D, Park S, Yoo H, Park S, Kim J, Yum K, Kim K, Kim H*, Overcoming anticancer resistance by photodynamic therapy-related efflux pump deactivation and ultrasound-mediated improved drug delivery efficiency, Nano Convergence 2020 7:30 (https://doi.org/10.1186/s40580-020-00241-8)
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Kim HM, Ha S, Hong HK, Hwang Y, Kim P, Park S, Park YJ, Park KH, Kim H, Woo SJ, Intraocular distribution and kinetics of intravitreally injected antibodies and nanoparticles in rabbit eyes, Translational vision science & technology 2020 May, Vol.9, 20 doi:https://doi.org/10.1167/tvst.9.6.20
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Han H, Kim D, Jang Y, Seo M, Kim K, Lee JB, Kim H*, Focused ultrasound-triggered chemo-gene therapy with multifunctional nanocomplex for enhancing therapeutic efficacy, J Control Release 2020 June 10;322:346-356 [상위 3.3%]
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Jang Y, Lee H, Kim D, Jang Y, Park S, Kim GE, Lee HJ, Kim HJ, Kim H*, Development of an Ultrasound Triggered Nanomedicine-Microbubble Complex for Chemo-Photodynamic-Gene Therapy, Nanomedicine: Nanotechnology, Biology, and Medicine 2020 Apr 8;27:102194 [IF 5.57]
[2019]
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Kim H, Lee H, Kim H, Chang JH*, High-sensitivity photoacoustic imaging using dual-modal ultrasound-photoacoustic contrast agents to eliminate non-targeted photoacoustic signals, (Submitted),
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Lee JH, Moon H, Han H, Lee I, Kim D, Lee HJ, Ha SW, Kim H*, Chung JW*, Antitumor Effects of Intra-Arterial Delivery of Albumin-Doxorubicin Nanoparticle Conjugated Microbubbles Combined with Ultrasound-Targeted Microbubble Activation on VX2 Rabbit Liver Tumors, Cancers 2019, 11(4), 581 [IF 6.162]
* Co-corresponding Author
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Kim H, Lee H, Moon H, Kang J, Jang Y, Kim D, Kim J, Huynh E, Zheng G, Kim H*, Chang JH*, Resonance-based frequency-selective amplification for increased photoacoustic imaging sensitivity, ACS Photonics (Accepted) [IF 6.880]
* Co-corresponding Author
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Lih E, Park W, Park KW, Chun SY, Kim H, Joung YK, Kwon TG, Hubbell JA, Han DK, A Bioinspired Scaffold with Anti-Inflammatory Magnesium Hydroxide and Decellularized Extracellular Matrix for Renal Tissue Regeneration, ACS Cent Sci. 2019 Mar 27;5(3):458 - 467
[2018]
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Lee H, Jang Y, Park S, Jang H, Park E, Kim HJ, Kim H*, Development and Evalulation of A CEACAM6 Targeting Theranostic Nanomedicine for the Photoacoustic-Based Diagnosis and Chemotherapy of Metastatic Cancer, Theranostics 2018 Jul 30;8(15):4247-4261 [IF 8.537, 상위 3.3%]
* inside cover http://www.thno.org/cover/v8i15.pdf
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Lee H, Han J, Shin H, Han H, Na K*, Kim H*, Combination of Chemotherapy and Photodynamic Therapy for Cancer Treatment with Sonoporation Effects, J Control Release 2018 Aug 10;283:190-199 [상위 3.9%]
* Co-corresponding Author
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Lee S, Lee H, Han H, Yoo H, Kim H, Chang JH, Kim H*, External Stimuli-responsive Melanin-like Nanoparticles for Photoacoustic Imaging-guided Therapy, Sci. Adv. Mater. 2018 May 1;10(5):665-673
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Choi D, Jeon S, You DG, Um W, Kim JY, Yoon HY, Chang H, Kim DE, Park JH, Kim H, Kim K, Iodinated Echogenic Glycol Chitosan Nanoparticles for X-ray CT/US Dual Imaging of Tumor, Nanotheranostics 2018 Jan 1;2(2):117-127
[2017]
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Kim SE, Lee BR, Lee H, Jo SD, Kim H, Won YY, Lee J, Near-Infrared Plasmonic Assemblies of Gold Nanoparticles with Multimodal Function for Targeted Cancer Theragnosis, Sci Rep 2017 Dec 11;7(1):17327-17336
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Han H, Lee H, Kim K*, Kim H*, Effect of High Intensity Focused Ultrasound (HIFU) in conjunction with a nanomedicine-microbubble complex for enhanced drug delivery, J Control Release 2017 Nov 28;266:75-86. [상위 3.9%]
* Co-corresponding Author
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Ryoo NK, Lee J, Lee H, Hong HK, Kim H, Lee JB, Woo SJ, Park K*, Kim H*, Therapeutic effects of a novel siRNA-based anti-VEGF (siVEGF) nanoball for the treatment of choroidal neovascularization, Nanosclae 2017 Oct 19;9(40):15461-15469
*Co-corresponding Author
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Lee JE, Kim KL, Kim D, Yeo Y, Han H, Kim MG, Kim SH, Kim H, Jeong JH, Suh W, Apatinib-loaded nanoparticles suppress vascular endothelial growth factor-induced angiogenesis and experimental corneal neovascularization, Int J Nanomedicine 2017;12:4813-4822
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Moon H, Kim H, Sim C, Lee H, Lee M, Chang JH, Lee HJ, Kim H*, Non-Invasive Tumor Therapy by Indocyanine Green and Paclitaxel Doubly Loaded Nanoparticles Using Photoacoustic Imaging, Sci. Adv. Mater. 2017; 9: 1177 - 1186
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Moon H, Kang J, Lee H, Lee M, Chang JH, Lee JH, Kim H*, Theragnostic nanodroplets for photoacoustic and ultrasound signal amplification and optically triggered vaporization-induced drug release, J. Nanosci. Nanotechnol. 2017;17:7978-7985
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Lee H, Kim H, Han H, Lee M, Lee S, Yoo H, Chang JH*, Kim H*, Microbubbles Used for Contrast Enhanced Ultrasound and Theragnosis: A Review of Principles to Applications, Biomed Eng Lett. 2017;7:59-69
* Co-corresponding Author
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Lee S, Han H, Koo H, Na JH, Yoon HY, Lee HK, Lee H, Kim H, Kwon IC, Kim K, Extracellular matrix remodeling in vivo for enhancing tumor-targeting efficiency of nanoparticle drug carriers using the pulsed high intensity focused ultrasound, J Control Release 2017 Feb 28 [Epub ahead of print]
[2016]
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Lee H, Kim H, Nguyen TP, Chang JH, Kim SY, Kim H*, Kang E *, Nanocomposites of Molybdenum Disulfide/Methoxy Polyethylene Glycol-co-Polypyrrole for Amplified Photoacoustic Signal, ACS Appl Mater Interfaces. 2016 Nov 2;8(43):29213-29219 [상위 9.2% 논문]
* Co-corresponding Author
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Han H, Son S, Son S, Kim N, Yhee JY, Lee JH, Choi JS, Joo CK, Lee H, Lee D, Kim WJ, Kim SH, Kwon IC, Kim H*, Kim K*, Reducible Polyethylenimine Nanoparticles for Efficient siRNA Delivery in Corneal Neovascularization Therapy, Macromol Biosci. 2016 Nov;16(11):1583-1597
* Co-corresponding Author
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Lih E, Park KW, Chun SY, Kim H, Kwon TG, Joung YK, Han DK, Biomimetic Porous PLGA Scaffolds Incorporating Decellularized Extracellular Matrix for Kidney Tissue Regeneration, ACS Appl Mater Interfaces. 2016 Aug 24; 8(33):21145-54 [상위 9.2% 논문]
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Lee J, Ryoo N, Han H, Hong HK, Park JY, Park SJ, Kim Y, Sim C, Kim K, Woo SJ, Park KH, Kim H, An anti-VEGF polysiRNA polyplex for the treatment of choroidal neovascularization, Mol. Pharmaceutics 2016 Jun 6;13(6):1988-95
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Na JH, Lee S, Han H, Lee KE, Han SJ, Choi SH, Kim H, Lee S, Kwon IC, Choi K, Kim K, T1-weighted MR imaging of liver tumor by gadolinium-encapsulated glycol chitosan nanoparticles without non-specific toxicity in normal tissues, Nanoscale. 2016 May;8(18):9736-9745 [상위 8% 논문]
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Kim J, Kim H, Moon H, Lee H, Chang JH, Kim J, Kim H, Multifunctional theranostic nanomedicine for photoacoustic imaging-guided combination tumor treatment, J Nanosci Nanotechnol. 2016;16(11):11903-11910
[2015]
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Moon H, Kang J, Sim C, Kim J, Lee H, Ha K, Chang JH, Kim H, Multifunctional theranostic contrast agent for photoacoustics-and ultrasound-based tumor diagnosis and ultrasound-stimulated local tumor therapy, J Controlled Release. 2015 Oct 9;218:63-71 [상위 3.9% 논문]
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Han DJ, Kim H*, Yeom S*, Nonspecific Mouse Hepatitis Virus Positivity of Genetically Engineered Mice Determined by ELISA, Biomed Sci Lett, 2015;21(1):9-14 * Co-corresponding Author
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Moon H, Kumar D, Kim H, Sim C, Chang JH, Kim JM, Kim H*, Lim DK*, Amplified photoacoustic performance and enhanced photothermal stability of reduced grapheme oxide coated gold nanorods for sensitive photoacoustic imaging, ACS Nano. 2015 Mar 24;9(3):2711-2719 * Co-corresponding Author [상위 3.9% 논문]
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Kim KE*, Jang I*, Moon H, Kim YJ, Jeoung JW, Park KH, Kim H, Multi-Neuroprotective Effects of Human Serum Albumin Nanoparticles Loaded with Brimonidine on Retinal Ganglion Cells in Optic Nerve Crush Model, Invest Ophthalmol Vis Sci 2015 Aug 1;56(9):5641-5649 * Equally Contributed [상위 14% 논문]
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Sim C, Kim H, Moon H, Chang JH, Kim H, Photoacoustics-based nanomedicine for cancer diagnosis and therapy, J Controlled Release, 2015 Feb 17;203C:118-125 [상위 3.9% 논문]
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Moon H, Yoon C, Lee TW, Ha K, Chang JH, Song T, Kim K, Kim H, Therapeutic Ultrasound Contrast Agent for the Enhancement of Tumor Diagnosis and Tumor Therapy, J Biomed Nanotechnol. 2015 11(7):1183-1192
[상위 12% 논문]
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Han DJ, Kim H, Rapid Detection of Methicillin Resistant Staphylococcus aureus Based on Surface Enhanced Raman Scattering, Korean J Clin Lab Sci, 2014, 46(4):136-139
[2014]
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Oh KS, Han H, Yoon BD, Lee M, Kim H, Seo DW, Seo JH, Kim K, Kwon IC, Yuk SH, Effect of HIFU treatment on tumor targeting efficacy of decetaxel-loaded Pluronic nanoparticles, Colloids Surf B Biointerfaces, 2014 Jul 1;119:137-144
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Ahn SJ, Ahn J, Park S, Kim H, Hwang DJ, Park JH, Park JY, Chung JY, Park KH, Woo SJ, Intraocular Pharmacokinetics of Ranibizumab in Vitrectomized versus Non-vitrectomized Eyes, Invest Ophthalmol Vis Sci, 2014 Jan 29;55(1):567-573
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Moon H, Han H, Lee SS, Kim H, A novel center-of-mass method to measure fluid velocity with MRI, Biomedical Signal Processing and Control, 2014 Jan;9:32-36
[2013]
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Han D, Hong J, Kim HC, Sung JH, Lee JB, Multiplexing Enhancement for the Detection of Multiple Pathogen DNA, J Nanoscience Nanotechnol. 2013, Nov;13:7295-7299
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Han D, Hong J, Kim HC, Sung JW, Lee JB, Aptamer-Based Microspheres for Highly Sensitive Protein Detection Using Fluorescently-Labeled DNA Nanostructures, J Nanoscience Nanotechnol. 2013 Nov;13:7259-7263
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Han DJ, Kim JB, Park SY, Yang MG, KIM H., Growth inhibition of hepatocellular carcinoma Huh7 cells by Lactobacillus casei extract, Yonsei Med J. 2013 Sep;54(5):1186-93
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Lee JB, Kim H, Control of nanoparticles on branched DNA nanostructures, J Biomed Nanotechnol. 2013 Jul;9(7):1245-9
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Moon H, Yu J, Park S, Chang JH, Song TK, Kim H, Narrow size distribution of microbubbles for enhancement of harmonic imaging, J Biomed Nanotechnol. 2013 May;9(5):845-8
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Ahn J, Kim H, Woo SJ, Park JH, Park S, Hwang DJ, Park KH, Pharmacokinetics of intravitreally injected bevacizumab in vitrectomized eyes, J Ocul Pharmacol Ther. 2013 Sep;29(7):612-8
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Lee H, Kim JB, Park SY, Kim SS, Kim H, Combination effect of paclitaxel and hyaluronic acid on cancer stem-like side population cells, J Biomed Nanotechnol. 2013 Feb;9(2):299-302
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Lee JB, Kim H, Stability of DNA nanostructures by junction penalty, J Biomed Nanotechnol. 2013 Apr;9(4):644-8
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Lee H, Park S, Kim JB, Kim J, Kim H, Entrapped doxorubicin nanoparticles for the treatment of metastatic anoikis-resistant cancer cells, Cancer Lett. 2013 May;332(1):110-9
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Lim J, Duong T. Do N, Do P, Kim J, Kim H, El-Rifai W, Ruley HE, Jo D, Antitumor activity of cell-permeable RUNX3 protein in gastric cancer cells, Clin Cancer Res. 2013 Feb;19(3):680-90
(2013년 이전 연구성과도 조만간 정리하도록 할게요)